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Tilvestamab

Cat. No. M25009

All AbMole products are for research use only, cannot be used for human consumption.

Tilvestamab Structure
Synonym:

BGB149

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Quality Control & Documentation
Biological Activity

Tilvestamab (BGB149) is a humanized anti-AXL antibody that blocks AXL-mediated cell signaling. Tilvestamab significantly inhibits Gas6-induced AXL activation in 786-0-Luc RCC cells and inhibits downstream AKT phosphorylation. Tilvestamab can be used in cancer research, particularly in AXL overexpressing renal cell carcinomas.

Chemical Information
CAS Number 2226775-26-2
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Tony J Chen, et al. Physiol Rep. AXL targeting by a specific small molecule or monoclonal antibody inhibits renal cell carcinoma progression in an orthotopic mice model

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  Catalog
Abmole Inhibitor Catalog




Keywords: Tilvestamab, BGB149 supplier, TAM Receptor, inhibitors, activators

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