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Thioflavin T is a widely used dye for visualizing and is a cationic Benzothiazole dye that shows enhanced fluorescence upon binding to amyloid in tissue sections. In the presence of amyloid fibrils, thioflavine T fluoresced brightly at the excitation and emission maxima of 450 and 482 nm, respectively, and the fluorescence change was linear from 0 to 2.0 micrograms/ml amyloid fibrils.
| Molecular Weight | 318.86 |
| Formula | C17H19ClN2S |
| CAS Number | 2390-54-7 |
| Solubility (25°C) | Water 5 mg/mL DMSO 16 mg/mL |
| Storage | 2-8°C, protect from light, dry, sealed |
[1] Ritu Khurana, et al. J Struct Biol. Mechanism of thioflavin T binding to amyloid fibrils
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