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TH10785 is a DNA glycosylase 1 (OGG1) activator, TH10785 can interact with the phenylalanine-319 and glycine-42 amino acids of OGG1 and increase the enzyme activity, generates β, δ-lyase enzymatic function. TH10785 can control the catalytic activity mediated by a nitrogen base within its molecular structure. TH10785 can be used for the research of various diseases and aging connected with DNA oxidative lesions.
Molecular Weight | 267.37 |
Formula | C17H21N3 |
CAS Number | 1002801-51-5 |
Form | Solid |
Solubility (25°C) | DMSO ≥ 100 mg/mL |
Storage | Powder -20°C |
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