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Tetrabenazine mesylate

Cat. No. M30634

All AbMole products are for research use only, cannot be used for human consumption.

Tetrabenazine mesylate Structure
Synonym:

Ro 1-9569 mesylate

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Quality Control & Documentation
Biological Activity

Tetrabenazine (Ro 1-9569) mesylate is a reversible inhibitor of the vesicular monoamine transporter VMAT2 with the Kd value of 1.34 nM. Tetrabenazine mesylate can be used for research on diseases related to hyperactive movement disorders such as Huntington's disease.

Chemical Information
Molecular Weight 413.53
Formula C20H31NO6S
CAS Number 804-53-5
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Manish Kumar, et al. Naunyn Schmiedebergs Arch Pharmacol. Exploring the anti-stress effects of imatinib and tetrabenazine in cold-water immersion-induced acute stress in mice

[2] Daniel A Hussar, et al. Consult Pharm. 2018 New Drug Update

[3] Cristiano Termine, et al. Int Rev Neurobiol. Emerging treatment strategies in Tourette syndrome: what's in the pipeline?

[4] J H Moss, et al. Can J Psychiatry. Iatrogenic parkinsonism in Huntington's chorea

[5] M J Benvenga, et al. J Pharmacol Toxicol Methods. An in vivo alpha-2 assay reversal of opioid-induced muscular rigidity and neuroleptic-induced ptosis

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Keywords: Tetrabenazine mesylate, Ro 1-9569 mesylate supplier, Monoamine Transporter, inhibitors, activators

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