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Tenatumomab

Cat. No. M24652

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Tenatumomab Structure
Synonym:

ST2146

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Quality Control & Documentation
Biological Activity

Tenatumomab (ST2146) is a murine monoclonal antibody against tenascin-C. And tenascin-C, the large extracellular glycoprotein, is overexpressed in cancer. Tenatumomab has been used for Pretargeted Antibody Guided Radioimmunotherapy (PAGRIT), and delivering radionuclides to tumors via PAGRIT and direct 131Iodine labeling approach.

Chemical Information
CAS Number 1412891-40-7
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Giuseppe Giannini, et al. Bioorg Med Chem. Synthesis and preliminary in vitro evaluation of DOTA-Tenatumomab conjugates for theranostic applications in tenascin expressing tumors

[2] Giuseppe Gritt, et al. Oncotarget. Correction: Evaluation of tenascin-C by tenatumomab in T-cell non-Hodgkin lymphomas identifies a new target for radioimmunotherapy

[3] Giuseppe Gritti, et al. Oncotarget. Evaluation of tenascin-C by tenatumomab in T-cell non-Hodgkin lymphomas identifies a new target for radioimmunotherapy

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Keywords: Tenatumomab, ST2146 supplier, inhibitors, activators

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