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TAT-Gap19 

Cat. No. M28551

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TAT-Gap19  Structure
Size Price Availability Quantity
1mg USD 210  USD210 In stock
5mg USD 600  USD600 In stock
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Quality Control & Documentation
Biological Activity

TAT-Gap19, a Cx mimetic peptide, is a specific connexin43 hemichannel (Cx43 HC) inhibitor. TAT-Gap19 does not inhibits the corresponding Cx43 GJCs. TAT-Gap19 traverses the blood-brain barrier and alleviate liver fibrosis in mice.

Chemical Information
Molecular Weight 2703.25
Formula C119H212N46O26
CAS Number 1507930-54-2
Form Solid
Solubility (25°C) Water 50 mg/mL (ultrasonic)
Storage Store at ≤ -20°C, dry, sealed
References

[1] Meixi Quan, et al. Circ Res. MST1 Suppresses Disturbed Flow Induced Atherosclerosis

[2] Hailong Yu, et al. J Neuroinflammation. Targeting connexin 43 provides anti-inflammatory effects after intracerebral hemorrhage injury by regulating YAP signaling

[3] Raghda Ramadan, et al. Front Pharmacol. Connexin43 Hemichannel Targeting With TAT-Gap19 Alleviates Radiation-Induced Endothelial Cell Damage

[4] Laura Walrave, et al. Glia. Inhibition of astroglial connexin43 hemichannels with TAT-Gap19 exerts anticonvulsant effects in rodents

[5] Sara Crespo Yanguas, et al. Int J Mol Sci. TAT-Gap19 and Carbenoxolone Alleviate Liver Fibrosis in Mice

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Keywords: TAT-Gap19  supplier, inhibitors, activators

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