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SR144528 is a potent and highly selective cannabinoid CB2 receptor inverse agonist. SR144528 exhibited a Ki of 0.6 nM at CB2 compared to 400 nM at the related CB1 receptor.
| Molecular Weight | 476.05 |
| Formula | C29H34ClN3O |
| CAS Number | 192703-06-3 |
| Solubility (25°C) | DMSO: 10 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Dragos Apostu, et al. Cannabinoids and bone regeneration
[3] Douglas Thewke, et al. AM-251 and SR144528 are acyl CoA:cholesterol acyltransferase inhibitors
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