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Soyasaponin-Bd

Cat. No. M4159
Soyasaponin-Bd Structure
Synonym:

Sandosaponin A

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5mg USD 700  USD700 Out of stock
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Quality Control & Documentation
Biological Activity

Soyasaponin-Bd

Chemical Information
Molecular Weight 957.1
Formula C48H76O19
CAS Number 135272-91-2
Solubility (25°C) 10 mM in DMSO
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Francesco Balestri, et al. Soyasaponins from Zolfino bean as aldose reductase differential inhibitors

[2] Tae Joung Ha, et al. Rapid characterisation and comparison of saponin profiles in the seeds of Korean Leguminous species using ultra performance liquid chromatography with photodiode array detector and electrospray ionisation/mass spectrometry (UPLC-PDA-ESI/MS) analysis

[3] Jung Nam Choi, et al. Metabolomics revealed novel isoflavones and optimal cultivation time of Cordyceps militaris fermentation

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