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Somatostatin, also known as growth hormone-inhibiting hormone, is a naturally-occurring peptide hormone of 14 or 28 amino acid residues. Somatostatin is secreted by the D cells of the islets to inhibit the release of insulin and glucagon, and is also generated in the hypothalamus, where it inhibits the release of growth hormone and thyroid-stimulating hormones from the anterior pituitary.
Sequence: H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH (Disulfide bridge: Cys3-Cys14)
| Molecular Weight | 1637.88 |
| CAS Number | 51110-01-1 |
| Solubility (25°C) | Water 50 mg/mL |
| Storage | -20°C, sealed |
| Related Somatostatin Receptor Products |
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L-817818 is a potent and subtype-selective agonist of the somatostatin receptor. |
| NNC 26-9100
NNC 26-9100 is a selective somatostatin sst4 receptor full agonist (Ki: 6 nM, EC50: 2 nM). |
| (1R,1'S,3'R/1R,1'R,3'S)-L-054,264
(1R,1'S,3'R/1R,1'R,3'S)-L-054,264 is a selective non-peptide human somatostatin receptor subtype 2 (sst2) agonist. |
| TT-232
TT-232 (CAP-232), a somatostatin derivative, is a peptide SSTR1/SSTR4 agonist. |
| Cyclosomatostatin
Cyclosomatostatin is a potent somatostatin (SST) receptor antagonist. |
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