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Simvastatin acid (Tenivastatin) ammonium is a potent HMG-CoA reductase (HMGCR) inhibitor. Simvastatin acid ammonium reduces Indoxyl sulfate-mediated reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin acid ammonium can also modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene.
| Molecular Weight | 453.61 |
| Formula | C25H43NO6 |
| CAS Number | 139893-43-9 |
| Form | Solid |
| Solubility (25°C) | DMSO 11.11 mg/mL (ultrasonic and warming and heat to 60°C) |
| Storage | 4°C, dry, sealed |
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| Fluvastatin
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| Pravastatin lactone
Pravastatin lactone is a potent HMG-CoA inhibitor. |
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HMG-CoA Reductase-IN-1 is a HMG-CoA reductase inhibitor. |
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