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SDZ 224-015 

Cat. No. M28690

All AbMole products are for research use only, cannot be used for human consumption.

SDZ 224-015  Structure

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Quality Control & Documentation
Biological Activity

SDZ 224-015 is an orally active inhibitor of the interleukin-1 beta (IL-1β) converting enzyme and caspase-1. SDZ 224-015 possesses anti-COVID-19 activity, targeting Mpro (IC50 of 30 nM).

Chemical Information
Molecular Weight 652.52
Formula C30H35Cl2N3O9
CAS Number 161511-45-1
Form Solid
Solubility (25°C) DMSO 100 mg/mL (ultrasonic)
Storage -20°C, protect from light, dry, sealed
References

[1] Martin A Redhead, et al. Sci Rep. Bispecific repurposed medicines targeting the viral and immunological arms of COVID-19

[2] P R Elford, et al. Br J Pharmacol. Reduction of inflammation and pyrexia in the rat by oral administration of SDZ 224-015, an inhibitor of the interleukin-1 beta converting enzyme

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  Catalog
Abmole Inhibitor Catalog




Keywords: SDZ 224-015  supplier, IL Receptor/Related, inhibitors, activators

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