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SB 334867

Cat. No. M7263

All AbMole products are for research use only, cannot be used for human consumption.

SB 334867 Structure
Synonym:

SB334867A free base

Size Price Availability Quantity
5mg USD 92  USD92 In stock
10mg USD 150  USD150 In stock
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Quality Control & Documentation
Biological Activity

SB 334867 is a selective non-peptide orexin OX1 receptor antagonist. pKb values are 7.2 and < 5 for inhibition of intracellular Ca2+ release in CHO cells expressing human OX1 and OX2 receptors respectively. Blocks orexin-A induced grooming and feeding following systemic administration in vivo.

Chemical Information
Molecular Weight 319.32
Formula C17H13N5O2
CAS Number 792173-99-0
Form Solid
Solubility (25°C) DMSO 31.93 mg/mL (with gentle warming)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Kretschmer, et al. Eur J Pharmacol. Behavioral and neurochemical actions of the strychnine-insensitive glycine receptor antagonist, 7-chlorokynurenate, in rats.

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  Catalog
Abmole Inhibitor Catalog




Keywords: SB 334867, SB334867A free base supplier, OX Receptor, inhibitors, activators

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