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Sarafotoxin S6c is a highly selective ETB endothelin receptor agonist (Ki values are 0.29 and 28000 nM at ETB and ETA receptors respectively).
| Molecular Weight | 2516 |
| Formula | C103H147N27O37S5 |
| CAS Number | 121695-87-2 |
| Solubility (25°C) | Water 1 mg/mL |
| Storage | -20°C, dry, sealed, protect from light |
| Related Endothelin Receptor Products |
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| Zibotentan
Zibotentan (ZD4054) is a more selective and specific endothelin-A receptor (ETAR) antagonist with an IC50 value of 21 nM. |
| Sitaxsentan sodium
Sitaxsentan (TBC-11251) is an orally active, highly selective antagonist of endothelin A receptors. |
| Macitentan
Macitentan is an orally-active, tissue-targeting dual ET receptor antagonist. |
| Sulfisoxazole
Sulfisoxazole is a sulfonamide antibacterial with an oxazole substituent. Sulfisoxazole (Sulfafurazole) is an orally active endothelin receptor antagonist with IC50 values of 0.60 μM and 22 μM against endothelin receptor A and endothelin receptor B, respectively. Sulfisoxazole inhibits breast cancer exosome release by targeting endothelin receptor A. |
| Ro-46-2005
Ro 46-2005 is a novel synthetic non-peptide endothelin receptor antagonist, inhibits the specific binding of 125I-ET-1 to human vascular smooth muscle cells (ETA receptor) with IC50 of 220 nM. |
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