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Sanshodiol

Cat. No. M16969
Sanshodiol Structure
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Biological Activity

Sanshodiol

Chemical Information
CAS Number 54854-91-0
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Subhas Chandra Roy, et al. J Org Chem. Short and stereoselective total synthesis of furano lignans (+/-)-dihydrosesamin, (+/-)-lariciresinol dimethyl ether, (+/-)-acuminatin methyl ether, (+/-)-sanshodiol methyl ether, (+/-)-lariciresinol, (+/-)-acuminatin, and (+/-)-lariciresinol monomethyl e䲧盷Ỵ相㧀盶羹甗癰࠲Ɗ࠲à�甙嶁甕Ѐ瑖凶䀹뷼܇࠲à邈܇彿凷奋凷巫凷�܇܇彿凷܇塚凷܇ꍈ凼뷼܇學凷漸凼圔凷뷼܇圞凷圭凷䀹魸甝Ɗ Ɗ憠癠Ƈ펐࠳䓲甕皼癰펐࠳Ɗ 펐࠳à�甙펐࠳€䀹펔࠳€츫甖펔࠳΀펔࠳쭩甖펔࠳븰܇塞Item܇Count﫬濾폄࠳

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