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Samuraciclib hydrochloride

Cat. No. M10886

All AbMole products are for research use only, cannot be used for human consumption.

Samuraciclib hydrochloride Structure
Size Price Availability Quantity
1mg USD 135  USD135 In stock
5mg USD 300  USD300 In stock
10mg USD 450  USD450 In stock
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Quality Control & Documentation
Biological Activity

Samuraciclib (ICEC0942, CT7001) is a novel oral CDK7 inhibitor with an IC50 of 40 nM. It has IC50 values for other CDK proteins such as CDK1, CDK2, CDK5 and CDK9 as 45, 15, 230 and 30 times higher than that of CDK7 IC50, respectively. ICEC0942 (CT7001) promotes cell cycle blocking and apoptosis.

Chemical Information
Molecular Weight 430.98
Formula C22H31ClN6O
CAS Number 1805789-54-1
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Qijun Pan, et al. Org Biomol Chem. Copper-catalyzed three-component reaction of arylhydrazine hydrochloride, DABSO, and NFSI for the synthesis of arenesulfonyl fluorides

[2] Mahmut Atum, et al. Ideggyogy Sz. Delirium due to the use of topical cyclopentolate hydrochloride

[3] No authors listed. Carteolol

[4] S HIFT, et al. Wien Med Wochenschr. [Prothipendyl-hydrochloride, a new neuroleptic]

[5] S Groszkowski, et al. Pol J Pharmacol Pharm. 1-Haloacylpiperazines

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Keywords: Samuraciclib hydrochloride supplier, CDK, inhibitors, activators

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