Free shipping on all orders over $ 500

Sagittatoside B

Cat. No. M11079
Sagittatoside B Structure
Size Price Availability Quantity
5mg USD 560  USD560 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Sagittatoside B is a natural compound extracted from the plant Epimedium.

Chemical Information
Molecular Weight 646.64
Formula C32H38O14
CAS Number 118525-36-3
Form Solid
Storage 4°C, dry, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Yuping Shen, et al. Enzyme Microb Technol. Convenient preparation of sagittatoside B, a rare bioactive secondary flavonol glycoside, by recyclable and integrated biphase enzymatic hydrolysis

[2] Mengjie Sun, et al. Molecules. Development and Validation of a HPLC-MS/MS Method for Simultaneous Determination of Twelve Bioactive Compounds in Epimedium: Application to a Pharmacokinetic Study in Rats

[3] Bing-jie Zhao, et al. Planta Med. Beneficial Effects of a Flavonoid Fraction of Herba Epimedii on Bone Metabolism in Ovariectomized Rats

[4] Feng-Juan Xu, et al. Zhongguo Zhong Yao Za Zhi. [Study on preparation of sagittatoside B with epimedin B converted from cellulase]

[5] Yan Chen, et al. Molecules. Role of intestinal hydrolase in the absorption of prenylated flavonoids present in Yinyanghuo

Related Products
Isothiuronium

Isothiouronium is a functional group, it is the acid salt of isothiourea.

Sultosilic acid, piperazine salt

Sultosilic acid piperazine salt is a compound with lowering lipid activity. It causes significant shortening of the euglobulin lysis time and a significant diminution of platelet adhesiveness, as well as statistically significant decrease of triglycerides, total cholesterol, beta- and pre-beta-cholesterol and an increase of alpha-cholesterol.

Ipamorelin

Ipamorelin (NNC-26-0161) is a a novel and potent ghrelin mimetic peptide compound that counteracts glucocorticoid-induced decrease in bone formation of adult rats.

PRGL493

PRGL493 is a potent and selective long-chain acyl-CoA synthetase 4 (ACSL4) inhibitor. PRGL493 blocks cell proliferation and tumor growth in both breast and prostate cellular and animal models.

Hercynine

Hercynine is a natural product, found in the fine leaf algae, Schizosaccharomyces cerevisiae and honey bees, and is a precursor of L-(+)-ergothioneine.

  Catalog
Abmole Inhibitor Catalog




Keywords: Sagittatoside B supplier, inhibitors, activators


Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.