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-Sunvozertinib.gif)
(S)-Sunvozertinib ((S)-DZD9008) is the S-enantiomer of Sunvozertinib, EGFR exon 20 NPH and ASV insertion, EGFR L858R/T790M mutation and Her2 exon 20 YVMA insertion (IC50 was 51.2 nM, 51.9 nM, 1 nM and 21.2 nM, respectively). (S)-Sunvozertinib also inhibits BTK.
| Molecular Weight | 584.08 |
| Formula | C29H35ClFN7O3 |
| CAS Number | 2370013-49-1 |
| Solubility (25°C) | DMSO ≥ 40 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related EGFR/HER2 Products |
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| Matuzumab
Matuzumab (EMD 72000) is a humanized monoclonal antibody that binds tightly to EGFR. |
| AEE788
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