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S-Adenosyl-L-methionine disulfate tosylate

Cat. No. M11548

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S-Adenosyl-L-methionine disulfate tosylate Structure
Synonym:

Ademetionine disulfate tosylate; S-Adenosyl methionine disulfate tosylate; AdoMet disulfate tosylate

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100mg USD 90  USD90 In stock
500mg USD 290  USD290 In stock
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Quality Control & Documentation
Biological Activity

S-adenosyl-l-methionine disulfate tosylate (Ademetionine disulfate tosylate) is the main biomethyl donor synthesized in all mammalian cells, but is most abundant in liver. Ademetionine has anti-inflammatory activity and has been used in studies of chronic liver disease.

Chemical Information
Molecular Weight 766.79
Formula C22H34N6O16S4
CAS Number 97540-22-2
Form Solid
Solubility (25°C) DMSO ≥ 50 mg/mL
Water 30 mg/mL
Storage 4°C, protect from light, dry, sealed
References

[1] Jin Yang, et al. Clin Ther. Pharmacokinetic properties of S-adenosylmethionine after oral and intravenous administration of its tosylate disulfate salt: a multiple-dose, open-label, parallel-group study in healthy Chinese volunteers

[2] M Tsuji, et al. Jpn J Pharmacol. Protective effect of S-adenosyl-L-methionine against CCl4-induced hepatotoxicity in cultured hepatocytes

[3] M Tsuji, et al. Jpn J Pharmacol. Protective effects of S-adenosyl-L-methionine against enzyme leakage from cultured hepatocytes and hypotonic hemolysis

[4] G P Bray, et al. Hepatology. S-adenosylmethionine protects against acetaminophen hepatotoxicity in two mouse models

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Keywords: S-Adenosyl-L-methionine disulfate tosylate, Ademetionine disulfate tosylate; S-Adenosyl methionine disulfate tosylate; AdoMet disulfate tosylate supplier, Metabolite/Endogenous Metabolite, inhibitors, activators

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