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Rintodestrant

Cat. No. M29188

All AbMole products are for research use only, cannot be used for human consumption.

Rintodestrant Structure
Synonym:

G1T48

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Quality Control & Documentation
Biological Activity

Rintodestrant (G1T48) is an orally active, non-steroidal and selective estrogen receptor degrader. Rintodestrant (G1T48) is also a CDK4/6 inhibitor.

Chemical Information
Molecular Weight 462.49
Formula C26H19FO5S
CAS Number 2088518-51-6
Form Solid
Solubility (25°C) DMSO 50 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Ramsha Iqbal, et al. Clin Cancer Res. [18F]FDG and [18F]FES PET/CT Imaging as a Biomarker for Therapy Effect in Patients with Metastatic ER+ Breast Cancer Undergoing Treatment with Rintodestrant

[2] Ya-Chi Chen, et al. Expert Opin Investig Drugs. Latest generation estrogen receptor degraders for the treatment of hormone receptor-positive breast cancer

[3] Ramsha Iqbal, et al. J Nucl Med. Biodistribution of 18F-FES in Patients with Metastatic ER+ Breast Cancer Undergoing Treatment with Rintodestrant (G1T48), a Novel Selective ER Degrader

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  Catalog
Abmole Inhibitor Catalog




Keywords: Rintodestrant, G1T48 supplier, Estrogen Receptor, inhibitors, activators

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