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Resolvin E1

Cat. No. M30291

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Resolvin E1 Structure
Synonym:

RvE1

Size Price Availability
10ug USD 350  USD350 3-4 Weeks
25ug USD 700  USD700 3-4 Weeks
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Quality Control & Documentation
Biological Activity

Resolvin E1 (RvE1), a potent endogenous pro-resolving mediator of inflammation, is derived from omega-3 fatty acid eicosapentaenoic acid (EPA). Resolvin E1 is endogenously biosynthesized from EPA in the presence of Aspirin during the spontaneous resolution phase of acute inflammation, where specific cell-cell interactions occur. Resolvin E1 possesses unique counterregulatory actions that inhibit polymorphonuclear leukocyte (PMN) transendothelial migration. Resolvin E1 also acts as a potent inhibitor of leukocyte infiltration, dendritic cell migration, and IL-12 production.

Chemical Information
Molecular Weight 350.45
Formula C20H30O5
CAS Number 552830-51-0
Form Liquid
Storage -20°C
References

[1] Jenaro A Espitia-Corredor, et al. Biochim Biophys Acta Mol Basis Dis. Resolvin E1 attenuates doxorubicin-induced cardiac fibroblast senescence: A key role for IL-1β

[2] Fahad A Abdullatif, et al. Front Oral Health. Resolvin E1's Antimicrobial Potential Against Aggregatibacter Actinomycetemcomitans

[3] Guizhu Liu, et al. Hypertension. Resolvin E1 Attenuates Pulmonary Hypertension by Suppressing Wnt7a/β-Catenin Signaling

[4] Jie Chen, et al. Stem Cell Res Ther. Resolvin E1 accelerates pulp repair by regulating inflammation and stimulating dentin regeneration in dental pulp stem cells

[5] Gonzalo Artiach, et al. Circulation. Omega-3 Polyunsaturated Fatty Acids Decrease Aortic Valve Disease Through the Resolvin E1 and ChemR23 Axis

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Keywords: Resolvin E1, RvE1 supplier, Metabolite/Endogenous Metabolite, inhibitors, activators

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