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Recombinant Human Fetuin A (HEK293, C-6His)

Cat. No. M21644

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Human Fetuin A (HEK293, C-6His) Structure
Synonym:

FETUA; AHSG; Alpha-2-HS-Glycoprotein

Size Price Availability Quantity
10ug USD 166  USD166 In stock
50ug USD 380  USD380 In stock
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Quality Control & Documentation
  • Purity: >95%, Endotoxin < 1 EU/µg
  • COA
  • MSDS
Biological Activity

Recombinant Human Fetuin A (AHSG) is a glycoprotein that is composed of two subunits, the A and B chains, belongs to the Cystatin family of proteases inhibitors. It is highly expressed in embryonic cells and adult hepatocytes, and is expressed to a lesser extent in monocytes/macrophages. AHSG is an important circulating inhibitor of calcification in vivo, and is downregulated during the acute-phase response. Alpha-2-HS-Glycoprotein is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. In addition, AHSG may influence the resolution of inflammation by modulating the phagocytosis of apoptotic cells by macrophages. Recombinant Human Fetuin A (C-6His) is produced by Mammalian expression system and the target gene encoding Ala19-Val367 is expressed with a 6His tag at the C-terminus.

Chemical Information
Solubility (25°C) Reconstitute the lyophilized powder in distilled water to a concentration of 100μg/ml
Storage Stored at ≤ -20°C, stable for one year after receipt
References

[1] Kevin C J Yuen, et al. Endocr Pract. AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY GUIDELINES FOR MANAGEMENT OF GROWTH HORMONE DEFICIENCY IN ADULTS AND PATIENTS TRANSITIONING FROM PEDIATRIC TO ADULT CARE

[2] Konstantin Karmilin, et al. Sci Rep. Mammalian plasma fetuin-B is a selective inhibitor of ovastacin and meprin metalloproteinases

[3] Yu-Hsien Lin, et al. J Proteome Res. Similar Albeit Not the Same: In-Depth Analysis of Proteoforms of Human Serum, Bovine Serum, and Recombinant Human Fetuin

[4] Alexander N Kapustin, et al. Circ Res. Vascular smooth muscle cell calcification is mediated by regulated exosome secretion

[5] Annemarie Gagnon, et al. Clin Invest Med. Serum fetuin-A levels following recombinant human thyroid-stimulating hormone stimulation

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Keywords: Recombinant Human Fetuin A (HEK293, C-6His), FETUA; AHSG; Alpha-2-HS-Glycoprotein supplier, Cytokines and Growth Factors, inhibitors, activators

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