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R162

Cat. No. M14759

All AbMole products are for research use only, cannot be used for human consumption.

R162 Structure
Size Price Availability Quantity
5mg USD 93  USD93 In stock
10mg USD 148  USD148 In stock
25mg USD 283  USD283 In stock
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Quality Control & Documentation
Biological Activity

R162 is a potent inhibitor of glutamate dehydrogenase 1 (GDH1/GLUD1), with anti-cancer properties.

Chemical Information
Molecular Weight 264.28
CAS Number 64302-87-0
Solubility (25°C) DMF 6.25 mg/mL (ultrasonic and warming and heat to 60°C)
DMSO 5.2 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Erwin Vera, et al. Altered phosphatidylinositol regulation of mutant inwardly rectifying K + Kir7.1 channels associated with inherited retinal degeneration disease

[2] Lingtao Jin, et al. The PLAG1-GDH1 Axis Promotes Anoikis Resistance and Tumor Metastasis through CamKK2-AMPK Signaling in LKB1-Deficient Lung Cancer

[3] Anna Akhmanova, et al. Microtubule minus-end-targeting proteins

[4] Lingtao Jin, et al. Glutamate dehydrogenase 1 signals through antioxidant glutathione peroxidase 1 to regulate redox homeostasis and tumor growth

[5] Robert J Osborne, et al. RNA-dominant diseases

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Keywords: R162 supplier, inhibitors, activators

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