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Pyridostatin (RR82) hydrochloride is a G-quadruplex DNA stabilizing agent (Kd=490 nM). Pyridostatin hydrochloride promotes growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage. Pyridostatin hydrochloride targets the proto-oncogene Src. Pyridostatin hydrochloride reduced SRC protein levels and SRC-dependent cellular motility in human breast cancer cells.
| Molecular Weight | 778.94 |
| CAS Number | 1781882-65-2 |
| Form | Solid |
| Solubility (25°C) | Water 50 mg/mL |
| Storage | 2-8°C, sealed |
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