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Protoporphyrin IX

Cat. No. M10029

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Protoporphyrin IX Structure
Size Price Availability Quantity
50mg USD 35  USD35 In stock
100mg USD 55  USD55 In stock
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Quality Control & Documentation
Biological Activity

Protoporphyrin IX is the final intermediate in the heme biosynthetic pathway. Protoporphyrin IX acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma.

Chemical Information
Molecular Weight 562.66
Formula C34H34N4O4
CAS Number 553-12-8
Solubility (25°C) DMSO 2 mg/mL
Storage 2-8°C, protect from light, dry, sealed
References

[1] Yasushi Nakai, et al. Photodiagnosis Photodyn Ther. Protoporphyrin IX induced by 5-aminolevulinic acid in bladder cancer cells in voided urine can be extracorporeally quantified using a spectrophotometer

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