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Prostaglandin A2 (PGA2) is a endogenous metabolite derived from arachidonic acid, it plays a vital role in the induction of apoptosis. Prostaglandin A2 blocks the cell cycle progression of NIH 3T3 cells at the G1 and G2/M phase. Prostaglandin A2 induces p53-dependent apoptosis. Prostaglandin A2 also has antiviral activity. Prostaglandin A2 additionally acts as a vasodilator with natriuretic properties.
| Molecular Weight | 334.45 |
| Formula | C20H30O4 |
| CAS Number | 13345-50-1 |
| Solubility (25°C) | Soluble in methyl acetate (~10 mg/mL) |
| Storage | -20°C, dry, sealed |
[2] Su-Been Lee, et al. Biomolecules. Induction of p53-Dependent Apoptosis by Prostaglandin A2
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