Free shipping on all orders over $ 500

Polycaprolactone

Cat. No. M9377
Polycaprolactone Structure
Synonym:

PCL

Size Price Availability Quantity
5g USD 40  USD40 In stock
25g USD 90  USD90 In stock
50g USD 120  USD120 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Chemical Information
Formula (C6H10O2)n
CAS Number 24980-41-4
Storage 2-8°C, dry, protect from light, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Sara Liparoti, et al. Polycaprolactone/polyethylene-glycol capsules made by injection molding: A drug release modeling

[2] Nadeem Siddiqui, et al. Electropsun Polycaprolactone Fibres in Bone Tissue Engineering: A Review

[3] Mengen Zhang, et al. Oxygen-releasing polycaprolactone/calcium peroxide composite microspheres

[4] Swee-Hin Teoh, et al. Three-Dimensional Printed Polycaprolactone Scaffolds for Bone Regeneration Success and Future Perspective

[5] Marianne Labet, et al. Synthesis of polycaprolactone: a review

Related Products
Hercynine

Hercynine is a natural product, found in the fine leaf algae, Schizosaccharomyces cerevisiae and honey bees, and is a precursor of L-(+)-ergothioneine.

C24-Ceramide

C24 Ceramide (Lignoceric ceramide) is a naturally occurring ceramide and an integral part of the sphingomyelin cycle. C24 Ceramide (Lignoceric ceramide) stimulates the proliferation of basophilic erythroblasts, suggesting a possible role in erythrocyte maturation.

RNA-protein crosslinking (sulfhydryl addition) agent

RNA-protein crosslinking (sulfhydryl addition) agent is a thiolating agent that is useful in cross-linking proteins. Thiolan-2-imine hydrochloride is a reagent for the introduction of sulphydryl groups into oligosaccharides derived from asparagine-linked glycans.

Izeltabart

Izeltabart is a high-affinity humanized antibody targeting ADAM9. Izeltabart can be used as ADC Antibody for site-specific conjugation with Maytansinoid-based DM21-C to synthesize IMGC936, an Antibody-drug Conjugate with strong anti-cancer activity. IMGC936 exhibits cytotoxicity against ADAM9-positive human tumor cell lines and potent antitumor activity in xenograft tumor models.

Cofetuzumab

Cofetuzumab (PF-06523435) is a humanized IgG1-κ monoclonal antibody targeting PTK7.

  Catalog
Abmole Inhibitor Catalog




Keywords: Polycaprolactone, PCL supplier, inhibitors, activators


Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.