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Poly-L-lysine (MW 15000~30000)

Cat. No. M25527
Poly-L-lysine (MW 15000~30000) Structure
Size Price Availability Quantity
5mg USD 100  USD100 In stock
10mg USD 150  USD150 In stock
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Quality Control & Documentation
Biological Activity

Poly-L-lysine (MW 15000~30000)

Chemical Information
Formula (C6H12N2O2)n.xHBr
CAS Number 25988-63-0
Solubility (25°C) Water ≥ 30 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

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