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Poloxime 

Cat. No. M28838

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Poloxime  Structure

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Quality Control & Documentation
Biological Activity

Poloxime, a hydrolysis product of poloxin, is a non-ATP-competitive Plk1 inhibitor, with moderate Plk1 inhibitory activity.

Chemical Information
Molecular Weight 179.22
Formula C10H13NO2
CAS Number 17302-61-3
Form Solid
Solubility (25°C) DMSO ≥ 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Payam Zarrintaj, et al. Acta Biomater. Poloxamer: A versatile tri-block copolymer for biomedical applications

[2] Karim A Soliman, et al. Drug Discov Today. Poloxamer-based in situ gelling thermoresponsive systems for ocular drug delivery applications

[3] Unji Lee, et al. Xenobiotica. Pharmacokinetic alterations in poloxamer 407-induced hyperlipidemic rats

[4] Gilles Dumortier, et al. Pharm Res. A review of poloxamer 407 pharmaceutical and pharmacological characteristics

[5] Winter J Gibbs, et al. Ann Pharmacother. Purified poloxamer 188 for sickle cell vaso-occlusive crisis

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  Catalog
Abmole Inhibitor Catalog




Keywords: Poloxime  supplier, PLK, inhibitors, activators

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