Free shipping on all orders over $ 500

PKI-179

Cat. No. M1739

All AbMole products are for research use only, cannot be used for human consumption.

PKI-179 Structure
Size Price Availability
5mg USD 180  USD180 Out of stock
10mg USD 280  USD280 Out of stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

PKI-179 is an orally dual phosphatidylinositol-3-kinase (PI3K)/mammalian target of rapamycin (mTOR) inhibitor  with potential antineoplastic activity.

Chemical Information
Molecular Weight 488.54
Formula C25H28N8O3
CAS Number 1197160-28-3
Solubility (25°C) DMSO
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Venkatesan et al. Bioorg Med Chem Lett. PKI-179: an orally efficacious dual phosphatidylinositol-3-kinase (PI3K)/mammalian target of rapamycin (mTOR) inhibitor.

[2] Chen et al. J Org Chem. Stereoselective synthesis of an active metabolite of the potent PI3 kinase inhibitor PKI-179.

Related PI3K Products
PI3Kγ inhibitor AZ2 

PI3Kγ inhibitor AZ2 is a highly selective PI3Kγ inhibitor (The pIC50 value for PI3Kγ is 9.3).

NIBR-17 

NIBR-17 is a pan-class I PI3K inhibitor with suitable pharmacokinetic properties and inhibits tumor growth.

RV-1729 

RV-1729 is an inhibitor of the phosphatidylinositol 3-kinase-δ (PI3Kδ).

Vulolisib 

Vulolisib is a potent and orally active phosphatidylinositol 3-kinase (PI3K) inhibitor, with IC50 values of 0.2 nM, 168 nM, 90 nM and 49 nM for PI3Kα, PI3Kβ, PI3Kγ and PI3Kδ, respectively.

Vps34-IN-4 

Vps34-IN-4 is a potent, selective, and orally active inhibitor of VPS34.

  Catalog
Abmole Inhibitor Catalog




Keywords: PKI-179 supplier, PI3K, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.