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Piromelatine (Neu-P11) is a melatonin MT1/MT2 receptor agonist, serotonin 5-HT1A/5-HT1D agonist, and serotonin 5-HT2B antagonist. Piromelatine (Neu-P11) possesses sleep promoting, analgesic, anti-neurodegenerative, anxiolytic and antidepressant potentials. Piromelatine (Neu-P11) also possesses pain-related P2X3, TRPV1, and Nav1.7 channel-inhibition capacities.
| Molecular Weight | 312.32 |
| Formula | C17H16N2O4 |
| CAS Number | 946846-83-9 |
| Form | Solid |
| Solubility (25°C) | DMSO 250 mg/mL (ultrasonic) |
| Storage | 4°C, protect from light |
| Related Melatonin Receptor Products |
|---|
| DH97
DH97 is a potent and selective antagonist of MT2 melatonin receptor, with a pKi of 8.03 for human MT2. |
| 8-M-PDOT
8-M-PDOT (AH-002) is a selective melatonin MT2 receptor agonist. |
| 6-Chloromelatonin
6-Chloromelatonin is a potent melatonin receptor agonist with greater metabolic stability than melatonin. |
| Melatonin-d4
Melatonin-d4 |
| ACH-000143
ACH-000143 is a potent and orally active melatonin receptor agonist, with EC50 values of 0.06 nM and 0.32 nM for MT1 and MT2, respectively. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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