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Pimonidazole is a novel hypoxia marker for complementary study of tumor hypoxia and cell proliferation in tumor. Pimonidazole accumulates in hypoxic cells via covalent binding with macromolecules or by forming reductive metabolites after reduction of its nitro group, it can be used for qualitative and quantitative assessment of tumor hypoxia .
Molecular Weight | 290.75 |
CAS Number | 70132-51-3 |
Solubility (25°C) | Water 5 mg/mL (ultrasonic and warming and heat to 60°C) |
Storage | 2-8°C, dry, sealed |
[1] Kristina Y Aguilera, et al. Hypoxia Studies with Pimonidazole in vivo
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