Free shipping on all orders over $ 500

Pimonidazole hydrochloride

Cat. No. M14755

All AbMole products are for research use only, cannot be used for human consumption.

Pimonidazole hydrochloride Structure
Size Price Availability Quantity
10mg USD 50  USD50 In stock
25mg USD 110  USD110 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Pimonidazole is a novel hypoxia marker for complementary study of tumor hypoxia and cell proliferation in tumor. Pimonidazole accumulates in hypoxic cells via covalent binding with macromolecules or by forming reductive metabolites after reduction of its nitro group, it can be used for qualitative and quantitative assessment of tumor hypoxia .

Chemical Information
Molecular Weight 290.75
CAS Number 70132-51-3
Solubility (25°C) Water 5 mg/mL (ultrasonic and warming and heat to 60°C)
Storage 2-8°C, dry, sealed
References

[1] Kristina Y Aguilera, et al. Hypoxia Studies with Pimonidazole in vivo

[2] Kristine Gulliksrud, et al. Detection of different hypoxic cell subpopulations in human melanoma xenografts by pimonidazole immunohistochemistry

[3] C B Westbury, et al. Hypoxia can be detected in irradiated normal human tissue: a study using the hypoxic marker pimonidazole hydrochloride

[4] Ralph E Durand, et al. The fate of hypoxic (pimonidazole-labelled) cells in human cervix tumours undergoing chemo-radiotherapy

[5] Johannes H A M Kaanders, et al. Pimonidazole binding and tumor vascularity predict for treatment outcome in head and neck cancer

Related Products
D-Allulose

D-Allulose (D-Psicose) is an ultralow-energy monosaccharide sugar. It is a C-3 epimer of D-fructose, and is present in small quantities in agricultural products and commercially-prepared carbohydrate complexes.

N,N-Dimethyltrifluoromethanesulfonamide

N,N-Dimethyltrifluoromethanesulfonamide (DMTMSA) is a trifluoromethanesulfonamide solvent.

Lucicebtide

Lucicebtide is a peptide antagonist of the transcription factor C/EBPβ, a key activator of the transcriptional program in immunosuppressive macrophages. Lucicebtide shows highly potent inhibition against C/EBPB-ATF5 association with IC50 of 24.6 nM in a competitive ELISA assay.

Eloralintide

Eloralintide (LY 3841136) is an AMYR agonist.

Gadoteric acid

Gadoteric acid is a macrocyclic, paramagnetic, gadolinium-based contrast agent that can be used for magnetic resonance imaging (MRI) of the brain, spine, and related tissues. Gadoteric acid is able to detect and visualize areas of blood-brain barrier disruption and abnormal vascular distribution.

  Catalog
Abmole Inhibitor Catalog




Keywords: Pimonidazole hydrochloride supplier, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.