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PF-CBP1 HCl is a highly selective inhibitor of the bromodomain of CREB-binding protein(CREBBP).It inhibits CREBBP and p300 bromodomains with IC50 of 125 and 363 nM respectively.
| Molecular Weight | 525.08 |
| Formula | C29H37ClN4O3 |
| CAS Number | 2070014-93-4 |
| Solubility (25°C) | DMSO 100 mg/mL Water 100 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Viral N Shah, et al. Diabetes Technol Ther. Standardized Hybrid Closed-Loop System Reporting
[2] Jrme Paillassa, et al. Curr Treat Options Oncol. Biology and Treatment of Hairy Cell Leukemia
[3] Phyu Thin Naing, et al. Hairy Cell Leukemia
[4] Enrico Tiacci, et al. J Clin Oncol. Genomics of Hairy Cell Leukemia
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| BAY-155
BAY-155 is a potent and selective menin-MLL tool inhibitor, with an IC50 of 8 nM. |
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| ISOX-DUAL
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