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Papain

Cat. No. M3826
Papain Structure
Synonym:

arbuz; caroid; nematolyt

Size Price Availability Quantity
100mg USD 70  USD70 In stock
500mg USD 140  USD140 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity 2000u/mg
  • COA
  • MSDS
Biological Activity

Papain is a cysteine protease of the peptidase C1 family.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 226.23
Formula C9H14N4O3
CAS Number 9001-73-4
Purity 2000u/mg
Solubility Soluble in water
Insoluble in most organic solvents
Storage 2-8°C, dry, protect from light, sealed
References

[1] Machado MN, et al. Front Physiol. Bone Marrow-Derived Mononuclear Cell Therapy in Papain-Induced Experimental Pulmonary Emphysema.

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Keywords: Papain, arbuz; caroid; nematolyt supplier, Cathepsin, inhibitors

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