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Pantoprazole sodium hydrate (BY10232 sodium hydrate) is an orally active and potent proton pump inhibitor (PPI). Pantoprazole sodium hydrate is also a potent H+/K+-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole sodium hydrate improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole sodium hydrate significantly increased tumor growth delay combined with Doxorubicin .
Molecular Weight | 432.37 |
Formula | C16H17F2N3NaO5.5S |
CAS Number | 164579-32-2 |
Solubility (25°C) | Water > 150 mg/mL DMSO 90 mg/mL |
Storage | 2-8°C, protect from light, dry, sealed |
[1] Laura Hoen, et al. Association of Drug Application and Hydration Status in Elderly Patients
[2] Chen Bei, et al. [Characterization and stability of S (-) pantoprazole sodium hydrates]
[4] V Zupancic, et al. Physical characterization of pantoprazole sodium hydrates
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