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Paltimatrectinib (compound I-147) is a potent tyrosine kinase inhibitor with an IC50 of <10 nM for tropomyosin kinases A (TrkA). Paltimatrectinib has the potential for cancer and inflammatory diseases.
| Molecular Weight | 434.37 |
| Formula | C20H15F5N6 |
| CAS Number | 2353522-15-1 |
| Form | Solid |
| Solubility (25°C) | DMSO 25 mg/mL (ultrasonic and warming and heat to 75°C) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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