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Pafolacianine

Cat. No. M25445

All AbMole products are for research use only, cannot be used for human consumption.

Pafolacianine Structure
Synonym:

OTL0038; OTL-38

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Quality Control & Documentation
Biological Activity

Pafolacianine, also known as OTL0038 and OTL-38, is a folate receptor-directing imaging agent. Pafolacianine (OTL 38) is used in detecting ovarian cancer lesions. Pafolacianine (OTL 38) accumulated at sites of inflammation in animal models.

Chemical Information
Molecular Weight 1326.49
Formula C61H67N9O17S4
CAS Number 1628423-76-6
Solubility (25°C) DMSO 20 mg/mL (ultrasonic and warming)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Inderpal S Sarkaria, et al. J Thorac Cardiovasc Surg. Pafolacianine for intraoperative molecular imaging of cancer in the lung: The ELUCIDATE trial

[2] Mihaela Elisabeta Dindere, et al. Int J Mol Sci. Intraoperative Tumor Detection Using Pafolacianine

[3] Stan Van Keulen, et al. Mol Imaging Biol. The Evolution of Fluorescence-Guided Surgery

[4] Janos L Tanyi, et al. J Clin Oncol. A Phase III Study of Pafolacianine Injection (OTL38) for Intraoperative Imaging of Folate Receptor-Positive Ovarian Cancer (Study 006)

[5] T Kramer, et al. Eur J Nucl Med Mol Imaging. Shining new light on lung cancer diagnosis using a pafolacianine molecular tracer

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Keywords: Pafolacianine, OTL0038; OTL-38 supplier, Fluorescent Dye, inhibitors, activators

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