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P32/98 

Cat. No. M28256

All AbMole products are for research use only, cannot be used for human consumption.

P32/98  Structure

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Quality Control & Documentation
Biological Activity

P32/98 a potent inhibitor of dipeptidyl peptidase IV with a Ki value of 130 nM. P32/98 improves glucose tolerance, insulin sensitivity and β-cell responsiveness in fatty Zucker rat model.

Chemical Information
Molecular Weight 202.32
Formula C9H18N2OS
CAS Number 136259-20-6
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Bao-Sheng Yu, et al. World J Pediatr. Glucagon-like peptide 1 based therapy for type 2 diabetes

[2] P Augstein, et al. Diabetes Obes Metab. Efficacy of the dipeptidyl peptidase IV inhibitor isoleucine thiazolidide (P32/98) in fatty Zucker rats with incipient and manifest impaired glucose tolerance

[3] E Wargent, et al. Diabetes Obes Metab. Improvement of glucose tolerance in Zucker diabetic fatty rats by long-term treatment with the dipeptidyl peptidase inhibitor P32/98: comparison with and combination with rosiglitazone

[4] Antje Meyer, et al. J Chromatogr B Analyt Technol Biomed Life Sci. Quantitative analysis of dipeptidyl peptidase inhibitor P32/98 and its main metabolite in rat, dog, mouse, monkey, human plasma and human urine using liquid chromatography-tandem mass spectrometry: application to pharmacokinetic evaluation

[5] J A Pospisilik, et al. Diabetes. Long-term treatment with the dipeptidyl peptidase IV inhibitor P32/98 causes sustained improvements in glucose tolerance, insulin sensitivity, hyperinsulinemia, and beta-cell glucose responsiveness in VDF (fa/fa) Zucker rats

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  Catalog
Abmole Inhibitor Catalog




Keywords: P32/98  supplier, Dipeptidyl Peptidase, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.


 
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