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Riviciclib hydrochloride (P276-00)

Cat. No. M2911

All AbMole products are for research use only, cannot be used for human consumption.

Riviciclib hydrochloride (P276-00)  Structure
Synonym:

Riviciclib hydrochloride

Size Price Availability
5mg USD 198  USD198 Out of stock
10mg USD 325  USD325 Out of stock
50mg USD 940  USD940 Out of stock
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Quality Control & Documentation
Biological Activity

Riviciclib hydrochloride (P276-00) is an effective CDK inhibitor, inhibiting CDK9-CyclinT1, CDK4-cyclin D1, CDK1-Cyclinb with IC50 values of 20 nM, 63 nM, respectively. 79 nM. Riviciclib hydrochloride (P276-00) has anti-tumor activity against Cisplatin resistant cells.

Chemical Information
Molecular Weight 438.3
Formula C21H20ClNO5.HCl
CAS Number 920113-03-7
Solubility (25°C) DMSO 70 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Shirsath NP, et al. Mol Cancer. P276-00, a cyclin-dependent kinase inhibitor, modulates cell cycle and induces apoptosis in vitro and in vivo in mantle cell lymphoma cell lines.

[2] Joshi KS, et al. Mol Cancer Ther. P276-00, a novel cyclin-dependent inhibitor induces G1-G2 arrest, shows antitumor activity on cisplatin-resistant cells and significant in vivo efficacy in tumor models.

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  Catalog
Abmole Inhibitor Catalog




Keywords: Riviciclib hydrochloride (P276-00) , Riviciclib hydrochloride supplier, CDK, inhibitors, activators

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