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Ozagrel hydrochloride is a potent and selective inhibitor of thromboxane (TXA2) synthetase (IC50 = 4 nM). Does not inhibit prostacyclin (PGI2) synthetase, cyclooxygenase or PGE2 isomerase (IC50 > 1 mM). Inhibits platelet aggregation in vitro and arachidonate-induced arterial contraction in vivo.
| Molecular Weight | 264.71 |
| Formula | C13H12N2O2.HCl |
| CAS Number | 74003-18-2 |
| Solubility (25°C) | Water 26.47 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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