Free shipping on all orders over $ 500

OXFBD04

Cat. No. M25521

All AbMole products are for research use only, cannot be used for human consumption.

OXFBD04 Structure

Price and Availability

For this product's availability, delivery time and price, please email [email protected] directly or click the "Inquiry Now" button below.


Quality Control & Documentation
Biological Activity

OXFBD04 is a potent and selective BRD4 inhibitor with an IC50 of 166 nM. OXFBD04 is a potent BET bromodomain ligand with additional modest affinity for the CREBBP bromodomain. OXFBD04 has anti-cancer activity.

Chemical Information
Molecular Weight 296.32
Formula C17H16N2O3
CAS Number 2231747-03-6
Solubility (25°C) DMSO >100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Noah R Flynn, et al. Metabolites. Bioactivation of Isoxazole-Containing Bromodomain and Extra-Terminal Domain (BET) Inhibitors

[2] Laura E Jennings, et al. Bioorg Med Chem. BET bromodomain ligands: Probing the WPF shelf to improve BRD4 bromodomain affinity and metabolic stability

Related Epigenetic Reader Domain Products
dBRD9 dihydrochloride 

dBRD9 dihydrochloride is a selective BRD9 PROTAC degrader.

BBC0403 

BBC0403 is a selective BRD2 inhibitor with Kds of 7.64 μM and 41.37 μM for BRD2 (BD2) and BRD2 (BD1), respectively.

BAY-155 

BAY-155 is a potent and selective menin-MLL tool inhibitor, with an IC50 of 8 nM.

FHT-1015 

FHT-1015 is a potent SMARCA4/SMARCA2 ATPase (BRG1 and BRM) inhibitor with IC50s of ≤10 nM.

ISOX-DUAL 

ISOX-DUAL is a dual CBP/BRD4 inhibitor with IC50 values of 0.65 μM and 1.5 μM for CBP and BRD4, respectively.

  Catalog
Abmole Inhibitor Catalog




Keywords: OXFBD04 supplier, Epigenetic Reader Domain, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.