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Oxazole yellow

Cat. No. M8667

All AbMole products are for research use only, cannot be used for human consumption.

Oxazole yellow Structure
Synonym:

YO-PRO-1; YP1

Size Price Availability Quantity
200uL USD 80  USD80 In stock
1mL USD 280  USD280 In stock
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Quality Control & Documentation
  • Purity: Biological Stain
  • COA
  • MSDS
Biological Activity

Oxazole yellow is a fluorescent cyanine dye that binds to DNA and is used to detect apoptotic cells. Oxazole yellow does not enter live cells. However, during apoptosis the cytoplasmic membrane becomes slightly permeable, allowing entry of the dye. Oxazole yellow is often used along with propidium iodide (catalog no. P4170), a DNA dead cell stain that does not enter either live or apoptotic cells. The λEx/λEm of Oxazole yellow is 491/509.

Chemical Information
Molecular Weight 629.32
Formula C24H29I2N3O
CAS Number 152068-09-2
Form Solution
Solubility (25°C) Water: 5 (warmed)
Storage -20°C, protect from light, sealed
References

[1] Karolina Kucharska, et al. Two Intercalation Mechanisms of Oxazole Yellow Dimer (YOYO-1) into DNA

[2] Chi Jin, et al. Molecular Dynamics of Oxazole Yellow Dye in its Ground and First Excited Electronic States in Solution and when Intercalated in dsDNA

[3] C U Murade, et al. Interaction of oxazole yellow dyes with DNA studied with hybrid optical tweezers and fluorescence microscopy

[4] M Wong, et al. Oxazole yellow homodimer YOYO-1-labeled DNA: a fluorescent complex that can be used to assess structural changes in DNA following formation and cellular delivery of cationic lipid DNA complexes

[5] L D Simon, et al. Oxazole yellow dye interactions with short DNA oligomers of homogeneous base composition and their hybrids

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Keywords: Oxazole yellow, YO-PRO-1; YP1 supplier, Fluorescent Dye, inhibitors, activators

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