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Oxaloacetic acid (2-Oxosuccinic acid) is a metabolic intermediate that involves pathways such as citric acid cycling, gluconeogenesis, urea cycling, glyoxylic acid cycling, amino acid synthesis, and fatty acid synthesis.
| Molecular Weight | 132.07 |
| Formula | C4H4O5 |
| CAS Number | 328-42-7 |
| Solubility (25°C) | DMSO ≥ 40 mg/mL Water 40 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[4] Philippe Icard, et al. Cancer Lett. ATP citrate lyase: A central metabolic enzyme in cancer
| Related Metabolite/Endogenous Metabolite Products |
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| Methionine sulfoximine
Methionine sulfoximine (2-Amino-4-(S-methylsulfonimidoyl)butanoic acid) is an irreversible inhibitor of glutamine synthetase. Methionine sulfoximine is able to affect the metabolism of glutamate and glutamine. |
| L-Glutamine-15N2
L-Glutamine-15N2 is the 15N-labeled L-Glutamine. L-Glutamine is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells. |
| S-Me-DM4
S-Me-DM4 is a metabolite of DM4 S-methylated by intracellular enzyme. |
| 4-Hydroxyestradiol
4-Hydroxyestradiol (4-Hydroxy-17β-estradiol) is an endogenous metabolite of Estradiol. 4-Hydroxyestradiol inhibits the binding of Estradiol to the estrogen receptor in a competitive manner, with a Ki of 0.48 nM. 4-Hydroxyestradiol is carcinogenic and shows mutagenic activity in breast epithelial cells. |
| Isolithocholic acid
Isolithocholic acid (β-Lithocholic acid) is an isomer of Lithocholic acid. Isolithocholic acid, a bile acid, is formed by microbial metabolism of Lithocholic acid or Lithocholic acid 3α-sulfate. |
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