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Orilanolimab

Cat. No. M24900

All AbMole products are for research use only, cannot be used for human consumption.

Orilanolimab Structure
Synonym:

SYNT001; ALXN1830

Size Price Availability Quantity
100ug USD 200  USD200 In stock
1mg USD 500  USD500 In stock
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Quality Control & Documentation
Biological Activity

Orilanolimab (SYNT001) is a humanized, de-immunized and FcRn-blocking monoclonal antibody. Orilanolimab blocks the interaction between FcRn and the Fc portion of IgG molecules. Orilanolimab impedes IgG IC activation of the FcRn-mediated adaptive immune function. And Orilanolimab disrupts the associated pathways related to IgG homeostasis and innate and adaptive immunity.

Chemical Information
CAS Number 2066544-85-0
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Faith A P Zeng, et al. Vet Dermatol. State-of-the-art review of human autoimmune blistering diseases (AIBD)

[2] L J Blumberg, et al. Sci Adv. Blocking FcRn in humans reduces circulating IgG levels and inhibits IgG immune complex-mediated immune responses

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  Catalog
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Keywords: Orilanolimab, SYNT001; ALXN1830 supplier, inhibitors, activators

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