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NVP 231 is a potent, selective and reversible ceramide kinase (CerK) inhibitor (IC50 = 12 nM in vitro). Displays selectivity for CerK over sphingosine kinases (IC50 ≥100 μM) and other lipid kinases.
| Molecular Weight | 431.55 |
| Formula | C25H25N3O2S |
| CAS Number | 362003-83-6 |
| Solubility (25°C) | DMSO 43.16 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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