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NUC-7738

Cat. No. M10487

All AbMole products are for research use only, cannot be used for human consumption.

NUC-7738 Structure
Synonym:

NUC7738

Size Price Availability Quantity
5mg USD 220  USD220 In stock
10mg USD 320  USD320 In stock
25mg USD 640  USD640 In stock
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Quality Control & Documentation
Biological Activity

NUC-7738 is an effective pro-apoptotic agent in cancer cells with effects on the NF-kappaB pathway. NUC-7738 induced a cytotoxic effect on a wide range of cancer cell lines with an IC50 in the low uM range (<10 uM). NUC-7738 has been well tolerated and has demonstrated encouraging signals of anti-cancer activity in solid tumours.

Chemical Information
Molecular Weight 568.52
Formula C26H29N6O7P
CAS Number 2348493-39-8
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Hagen Schwenzer, et al. Clin Cancer Res. The novel nucleoside analogue ProTide NUC-7738 overcomes cancer resistance mechanisms in vitro and in a first-in-human Phase 1 clinical trial

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Keywords: NUC-7738, NUC7738 supplier, inhibitors, activators

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