Free shipping on all orders over $ 500

NO-1886

Cat. No. M7950

All AbMole products are for research use only, cannot be used for human consumption.

NO-1886 Structure
Size Price Availability Quantity
5mg USD 50  USD50 In stock
10mg USD 75  USD75 In stock
25mg USD 140  USD140 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Lipoprotein lipase activator. Overexpression of lipoprotein lipase in transgenic rabbits leads to increased small dense LDL in plasma and promotes atherosclerosis. Long-term administration of NO-1886 protects against the development of experimental atherosclerosis in animals.

Chemical Information
Molecular Weight 451.25
Formula C19H20BrN2O4P
CAS Number 133208-93-2
Solubility (25°C) DMSO: ≥20 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Zong-Bao Wang, et al. NO-1886 ameliorates glycogen metabolism in insulin-resistant HepG2 cells by GSK-3β signalling

[2] Qinkai Li, et al. NO-1886 suppresses diet-induced insulin resistance and cholesterol accumulation through STAT5-dependent upregulation of IGF1 and CYP7A1

[3] Qishisan Wu, et al. NO-1886, a lipoprotein lipase activator, attenuates contraction of rat intestinal ring preparations

[4] Aki Nakamura, et al. NO-1886, a lipoprotein lipase activator, attenuates vascular smooth muscle contraction in rat aorta

[5] Weidong Yin, et al. Lipoprotein lipase activator NO-1886

Related Products
GAPDH-IN-1

GAPDH-IN-1 (GAPDH Inhibitor Compound F8) is a covalent inhibitor of GAPDH (IC50 = 39.31 µM). It viability of, and glucose metabolism in, HEK293 cells in a concentration-dependent manner.

O-acetylcamptothecin

O-acetylcamptothecin is a derivative of camptothecin, a naturally occurring alkaloid extracted from the bark of the Chinese tree Camptotheca acuminata. Camptothecin and its derivatives are primarily known for their potent anticancer properties, particularly through their action as inhibitors of topoisomerase I, an enzyme critical for DNA replication and transcription.

10-hydroxystearic acid

10-hydroxystearic acid is a hydroxy fatty acid.

SB-T-1214

SB-T-1214 is a new-generation taxoid. SB-T-1214 possesses significant activity against colon cancer spheroids induced by and enriched with drug resistant tumorigenic CD133high/CD44high cells and efficiently inhibited expression of the majority of stem cell-related genes.

NG-497

NG-497 is a selective human adipose triglyceride lipase (ATGL) inhibitor that targets the enzymatically active patatin-like domain of human ATGL.

  Catalog
Abmole Inhibitor Catalog




Keywords: NO-1886 supplier, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.