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NCTT-956

Cat. No. M8370

All AbMole products are for research use only, cannot be used for human consumption.

NCTT-956 Structure

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Quality Control & Documentation
Biological Activity

NCTT-956 is a very potent, specific inhibitor of 12-lipoxygenase (12-LO) activity, with an IC50 of 800 nM, no activity against 5-LO and greater than 25-fold selectivity over 15-LO. Specific inhibition of 12-LO by NCTT-956 in platelets blocks PKC activation, aggregation, granule secretion and αIIbB3 activation.

Chemical Information
Molecular Weight 357.38
Formula C17H15N3O4S
CAS Number 438575-88-3
Solubility (25°C) DMSO: 5 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
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  Catalog
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Keywords: NCTT-956 supplier, inhibitors, activators

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