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N-Lactoyl-Phenylalanine, a blood-derived signaling metabolite that can be induced by exercise, suppresses feeding and obesity and can be used in obesity research.
| Cell Experiment | |
|---|---|
| Cell lines | |
| Preparation method | |
| Concentrations | |
| Incubation time | |
| Animal Experiment | |
|---|---|
| Animal models | High-fat diet-induced obese mice (DIO mice) |
| Formulation | Dissolved in 18:1:1 (by volume) of saline/kolliphor EL/DMSO |
| Dosages | 50 mg/kg |
| Administration | Intraperitoneal injection |
| Molecular Weight | 237.25 |
| Formula | C12H15NO4 |
| CAS Number | 183241-73-8 |
| Form | Solid |
| Solubility (25°C) | Water 15 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[3] Jens Lund et al. Cell Metab. Outrunning obesity with Lac-Phe?
| Related Metabolite/Endogenous Metabolite Products |
|---|
| Isolithocholic acid
Isolithocholic acid (β-Lithocholic acid) is an isomer of Lithocholic acid. Isolithocholic acid, a bile acid, is formed by microbial metabolism of Lithocholic acid or Lithocholic acid 3α-sulfate. |
| 1-Palmitoyl-sn-glycero-3-phosphocholine
1-Palmitoyl-sn-glycero-3-phosphocholine is an lysophosphatidylcholine. 1-Palmitoyl-sn-glycero-3-phosphocholine exhibits proinflammatory activity. 1-Palmitoyl-sn-glycero-3-phosphocholine can be used in the research of atherosclerosis. |
| L-Citrulline DL-Malate
L-Citrulline DL-malate is an organic compound commonly used as a nutritional supplement. It boosts the body's production of nitrogen oxides, improves circulation and athletic performance, and reduces muscle fatigue. In addition, L-Citrulline DL-malate can be used in the field of agriculture to enhance plant immunity. |
| Creatine-d3
Creatine-d3 is the deuterium labeled Creatine. Creatine is an endogenous amino acid derivative, which plays an important role in cellular energy, especially in muscle and brain. |
| Creatinine-d3
Creatinine-d3 is a deuterium labeled Creatinine. Creatinine is a break-down product of creatine phosphate in muscle. |
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