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N-Acetylneuraminic acid

Cat. No. M7550

All AbMole products are for research use only, cannot be used for human consumption.

N-Acetylneuraminic acid Structure
Synonym:

NANA; Lactaminic acid

Size Price Availability Quantity
50mg USD 25  USD25 In stock
100mg USD 35  USD35 In stock
500mg USD 50  USD50 In stock
1g USD 60  USD60 In stock
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Quality Control & Documentation
Biological Activity

N-Acetylneuraminic acid is a nine-carbon, sialic acid monosaccharide commonly found in glycoproteins on cell membranes and in glycolipids such as gangliosides in mammalian cells. Studies suggest that N-Acetylneuraminic acid is useful biologically in neurotransmission, leukocyte extravasation, viral or bacterial infections and carbohydrate-protein recognition.

Protocol (for reference only)
Cell Experiment
Cell lines
Preparation method
Concentrations
Incubation time
Animal Experiment
Animal models Sprague-Dawley rats
Formulation -
Dosages 20 mg/kg
Administration i.p.
Chemical Information
Molecular Weight 309.27
Formula C11H19NO9
CAS Number 131-48-6
Solubility (25°C) Water 60 mg/mL
Storage -20°C, sealed
References

[1] Lee CG, et al. Sci Rep. Inhibition of poly-LacNAc biosynthesis with release of CMP-Neu5Ac feedback inhibition increases the sialylation of recombinant EPO produced in CHO cells.

[2] Wylie AD, et al. J Agric Food Chem. Quantitation of Sialic Acids in Infant Formulas by Liquid Chromatography-Mass Spectrometry: An Assessment of Different Protein Sources and Discovery of New Analogues.

[3] S E Carlson, et al. J Nutr. Oral and intraperitoneal administration of N-acetylneuraminic acid: effect on rat cerebral and cerebellar N-acetylneuraminic acid

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Keywords: N-Acetylneuraminic acid, NANA; Lactaminic acid supplier, Metabolite/Endogenous Metabolite, inhibitors, activators

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