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ML359 is a potent, selctive and reversible inhibitor of protein disulfide isomerase (PDI), with an IC50 of 250 nM. ML359 can prevent thrombus formation in vivo.
| Molecular Weight | 417.93 |
| Formula | C23H28ClNO4 |
| CAS Number | 1069858-99-6 |
| Form | Solid |
| Solubility (25°C) | DMSO 100 mg/mL (ultrasonic) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related PDI Products |
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| KSC-34
KSC-34, a covalent modifier of protein disulfide isomerase A1 (PDIA1), is also a selective and potent a-site inhibitor of PDIA1 with an IC50 of 3.5 μM. |
| PDI-IN-1
PDI-IN-1 is a cell-permeable human protein disulfide isomerase (PDI) inhibitor with an IC50 of 1.7 μM. |
| 3-Methyltoxoflavin
3-Methyltoxoflavin is a potent Protein disulfide isomerase (PDI) inhibitor, with an IC50 of 170 nM. |
| G6PDi-1
G6PDi-1 is a reversible and non-competitive glucose-6-phosphate dehydrogenase (G6PD) inhibitor with an IC50 of 0.07 μM. G6PDi-1 depletes NADPH most strongly in lymphocytes. G6PDi-1 markedly decreases inflammatory cytokine production in T cells. |
| LOC14
LOC14 is a potent PDI (protein disulfide isomerase) inhibitor with EC50 value of 500 nM. |
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